解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The clinical, pathologic, and immunologic features in nine cases of non-Hodgkin's lymphoma of the multilobated B-cell type are described. Clinical and phenotypic heterogeneity was observed in these B-cell neoplasms. A probable follicular center cell derivation for these cytologically unusual B-cell lymphomas is suppor...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(86)80131-9
更新日期:1986-06-01 00:00:00
abstract::T-lymphocyte subsets in peripheral blood, bronchoalveolar lavage fluid, and prescalenic lymph nodes from eight patients with sarcoidosis were evaluated with monoclonal antibodies. Both in lung and lymph nodes significant increases in helper T cells were demonstrated, except in patients with stage III pulmonary disease...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(86)80037-5
更新日期:1986-05-01 00:00:00
abstract::Two extraskeletal myxoid chondrosarcomas were examined by electron microscopy. In addition to the well-described ultrastructural features indicative of chondroblastic origin, both of these chondrosarcomas had unusual parallel microtubules packed within rough endoplasmic reticulum. This paper reviews the differential d...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(86)80036-3
更新日期:1986-05-01 00:00:00
abstract::Two cystic lesions that were lined by pseudostratified ciliated columnar epithelium containing goblet cells are described. Both lesions were found in the subarachnoid space between the vertebrobasilar arterial system and the brainstem. One cyst was an incidental finding in a patient who died of orbital phycomycosis. T...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(86)80467-1
更新日期:1986-04-01 00:00:00
abstract::Schistosoma haematobium infection is a common occurrence in Africa and the Middle East and is the world's leading cause of hematuria. Since more North Americans are venturing into endemic areas and more residents of endemic areas are seeking medical care in North America, pathologists must be able not only to diagnose...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(86)80456-7
更新日期:1986-04-01 00:00:00
abstract::A primary neoplasm of the proximal humerus in a 68-year-old woman was unique histologically in that it contained both malignant cartilaginous and squamous cell components. The epithelial differentiation was confirmed by the demonstration of keratin by immunohistochemical techniques and of basement membrane, tonofilame...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(83)80227-5
更新日期:1986-03-01 00:00:00
abstract::Fifty-three pure mucinous carcinomas of breast were studied, with long-term follow-up evaluation (average, 15 years) for 37. The mean age of the patients was 63 years. Long-term survival (Kaplan-Meier method) was 68 per cent, excluding non-tumor-related deaths. Median survival for the patients with fatal carcinomas wa...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(86)80152-6
更新日期:1986-01-01 00:00:00
abstract::The case of a patient in whom idiopathic thrombocytopenic purpura (ITP) was associated with diffuse splenic histiocytosis is described; the patient's subsequent sphingomyelinase level was at the lower limits of the normal range. The patient's splenic lecithin:sphingomyelin ratio was not significantly different from th...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80192-1
更新日期:1985-11-01 00:00:00
abstract::The introduction of chemotherapeutic agents directly into the proper hepatic artery via an indwelling catheter results in perfusion of the gallbladder, because the cystic artery is usually a branch of the right hepatic artery. Five gallbladders, removed two to 16 months after insertion of permanently implanted Infusai...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80275-6
更新日期:1985-10-01 00:00:00
abstract::Seven cases in which interstitial fibrosis developed in patients who had acute interstitial pneumonia were studied ultrastructurally to elucidate the pathogenesis of the interstitial thickening seen by light microscopy. Interstitial fibrosis is generally thought to result from fibroblast proliferation and collagen dep...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80279-3
更新日期:1985-10-01 00:00:00
abstract::The case of an infant with endocardial fibroelastosis and a coexistent anomalous right coronary artery that originated from the pulmonary trunk is presented. The causal relation between the two conditions is discussed. ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80138-6
更新日期:1985-09-01 00:00:00
abstract::Twenty-one childhood rhabdomyosarcomas were divided into three groups on the basis of cytologic composition. The tumors in group P consisted entirely of primitive mesenchymal cells, whereas those in groups M and W were characterized by the additional presence of numerous round rhabdomyoblasts and strap cells, respecti...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80256-2
更新日期:1985-08-01 00:00:00
abstract::Deposits found intrauterine contraceptive devices (IUDs) were studied by scanning electron microscopy, x-ray diffraction, and energy dispersive x-ray microanalysis. All seven devices, including five plastic and two copper IUDs, were coated with a crust containing cellular, acellular, and fibrillar material. The cellul...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80160-x
更新日期:1985-07-01 00:00:00
abstract::Two undifferentiated (embryonal) sarcomas of liver were studied ultrastructurally and immunohistochemically. Electron microscopic examination of the pleomorphic tumor cells revealed fibroblastic and histiocytic characteristics. There were no specific findings to support rhabdomyoblastic, leiomyoblastic, or epithelial ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80154-4
更新日期:1985-07-01 00:00:00
abstract::The case of an infant with the clinical features of bronchopulmonary dysplasia but with pathologic features unlike those usually associated with this condition is reported. The condition of this infant was probably related to respiratory therapy and may have been a variant of bronchopulmonary dysplasia. ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80113-1
更新日期:1985-06-01 00:00:00
abstract::A case of xanthomatosis of the small bowel is described. Beginning with the proximal jejunum, an 85-cm segment of small bowel was distorted by regularly spaced nodular accumulations of lipid-laden macrophages that expanded the submucosa and muscularis and extended to the serosal surface. The conditions often associate...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80237-9
更新日期:1985-04-01 00:00:00
abstract::In two patients with malignant germ cell tumors angiosarcoma developed through two apparently different mechanisms. In one case the angiosarcoma probably developed as a complication of therapeutic radiation, since radiation changes were demonstrated in tissue adjacent to the neoplasm and since the angiosarcoma was not...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80013-7
更新日期:1985-03-01 00:00:00
abstract::Renal glomerular disease characterized by the deposition of immunoglobulin light chains or monoclonal immunoglobulins was demonstrated by immunofluorescence microscopy in 11 patients. The most common histopathologic findings were those of mesangiocapillary glomerulonephritis, but considerable variability was observed....
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80017-4
更新日期:1985-03-01 00:00:00
abstract::Recent studies have indicated that some cases of fulminant hepatitis that were ostensibly type B were actually acute viral hepatitis, types B and delta, or persistent hepatitis, type B with superimposed acute delta infection. Histologic characterization of the various types has not yet been undertaken. Within ten to 3...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80012-5
更新日期:1985-03-01 00:00:00
abstract::The case of a biliary cystadenoma containing foci of cystadenocarcinoma is reported, along with the first electron microscopic description of this lesion. Both neoplastic and congenital origins have been implicated in the pathogenesis of biliary cystadenomas. In this case hamartomatous bile ducts were found, supportin...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80219-7
更新日期:1985-01-01 00:00:00
abstract::Autopsy studies of three premature siblings who died soon after birth with the neonatal myotonic dystrophy syndrome revealed pulmonary hypoplasia and congenital pleural effusions. Neither of these findings has been described previously in this condition. New ultrastructural findings include focal diaphragmatic myofibe...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80312-3
更新日期:1984-12-01 00:00:00
abstract::Bone marrow biopsy findings in 32 homosexual patients with the acquired immunodeficiency syndrome (AIDS) or prodromal AIDS are described. A high incidence (38 per cent) of nonparatrabecular lymphohistiocytic infiltrations containing irregular small lymphocytes was observed, as well as the presence of diffuse bone marr...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80248-8
更新日期:1984-11-01 00:00:00
abstract::Isolated submandibular adenopathy developed in a patient who had subacute erythroleukemia. Lymph node biopsy revealed a proliferation of immature cells and scattered foci of dyserythropoietic normoblasts. Since a review of the literature revealed no detailed description of an erythroleukemic lymph node infiltrate, a h...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80254-3
更新日期:1984-11-01 00:00:00
abstract::Immunofluorescence of formalin-fixed, paraffin-embedded tissues was performed to study the plasma cell population in 114 colonic specimens from 58 patients. Correlation of the histopathologic stage of disease activity with the isotypes and numbers of immunoglobulin-containing cells in the lamina propria demonstrated h...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80167-7
更新日期:1984-08-01 00:00:00
abstract::Tissues obtained from 600 routine autopsies were studied. Mineral oil lipidosis was present in the spleen (76 per cent), liver (45 per cent), bone marrow (26 per cent), and lymph nodes; more than 50 per cent of the lymph nodes from the mesentery, porta hepatis, and mediastinum were affected. Mineral oil and its metabo...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80163-x
更新日期:1984-08-01 00:00:00
abstract::Of the approximately 635 residents in each year of pathology training, about 165 are already meeting the Pathology Board's proposed requirement for a fifth year of resident training. The cost of a fifth year of training for the other 470 residents is estimated to be approximately $20 million. Options for avoiding this...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80159-8
更新日期:1984-08-01 00:00:00
abstract::A carcinoma of the urinary bladder with a distinct choriocarcinomatous component that developed in a postmenopausal woman was associated with high titers of circulating chorionic gonadotropin. The diagnosis was supported by histochemical demonstration of human chorionic gonadotropin in syncytial tumor giant cells and ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80173-2
更新日期:1984-08-01 00:00:00
abstract::In 112 unselected autopsies of adult patients without known pancreatic disease (except adult-onset diabetes mellitus), the pancreas was examined to establish the incidence and degree of such minor pancreatic lesions as lipomatosis, fibrosis, alterations of ducts and ductal epithelium, inflammatory infiltrates, focal n...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80294-4
更新日期:1984-07-01 00:00:00
abstract::Among 448 malignant epithelial tumors of the gallbladder, 19 were classified as oat cell carcinomas. Seventeen cases occurred in elderly women. Eighteen of the patients had cholelithiasis. The neoplasms were highly lethal, metastasizing early and causing death shortly after diagnosis. All 19 patients died as a direct ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80288-9
更新日期:1984-07-01 00:00:00
abstract::Decreases in true expenses in the hospital clinical laboratory consequent to reduced utilization were estimated from four models. Each category of direct expense was adjusted according to projections and confirmed to the extent possible by actual experience. No projections of reductions in indirect expenses were made....
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80002-7
更新日期:1984-06-01 00:00:00
abstract::A case of a tail in a 2-week-old infant is reported, and findings from a review of 33 previously reported cases of true tails and pseudotails are summarized. The true, or persistent, vestigial tail of humans arises from the most distal remnant of the embryonic tail. It contains adipose and connective tissue, central b...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80079-9
更新日期:1984-05-01 00:00:00
abstract::The absence of keratin staining in tumor cells from localized fibrous mesotheliomas in both paraffin-embedded and frozen sections with sensitive peroxidase-antiperoxidase and avidin-biotin techniques is described. In addition ot the absence of staining for whole-stratum corneum keratin proteins, sections were negative...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80077-5
更新日期:1984-05-01 00:00:00
abstract::Seminoma and sarcoidosis do not seem to be associated diseases, judging from epidemiologic data. The presence of these two diseases in the patient whose case is reported may have been coincidental. It was observed, however, that when the testis tumor appeared in this patient, the longstanding sarcoid lesions significa...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80041-6
更新日期:1984-04-01 00:00:00
abstract::Bioassay of hormones has a small but important role in defining the physiologic status of selected patients in whom immunoassay results do not correlate with clinical signs and symptoms. This article reviews three sensitive bioassays for hormones, which are based on 1) stimulation of adenylate cyclase in membrane prep...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/s0046-8177(84)80050-7
更新日期:1984-02-01 00:00:00
abstract::Three ovarian thecomas were studied by ultrastructural and immunohistochemical techniques. In each tumor, a small number of tumor cells stained for estradiol. Vacuolated as well as plump non-vacuolated tumor cells were positive, but spindle-shaped cells were negative. Ultrastructural examination showed two principle c...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80056-8
更新日期:1984-02-01 00:00:00
abstract::Cystic hygroma of the neck was observed in seven spontaneously aborted, severely autolyzed female fetuses. Four of five karyotyped cases had the 45,XO karyotype; one was a normal female, 46,XX. Diagnostic features associated with monosomy X in fetuses, which were observed in six of these cases, include large cystic hy...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80331-7
更新日期:1984-01-01 00:00:00
abstract::A case of clear cell sarcoma of tendons and aponeuroses arising in the elbow of a young woman is reported. Local recurrence and lymph node metastases occurred despite radiation therapy, chemotherapy, and amputation of the right arm, and the patient died of the tumor approximately ten months after the initial diagnosis...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(83)80267-6
更新日期:1983-12-01 00:00:00
abstract::Immunofluorescent staining of tissue from a lung tumor detected 12 years after excision of a primary malignant melanoma of the skin was negative for prekeratin and positive for vimentin, indicating that the tumor was not epithelial in origin and excluding carcinoma from the differential diagnosis. Complementary conven...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(83)80182-8
更新日期:1983-11-01 00:00:00
abstract::Renal biopsy specimens from 19 patients with asymptomatic hematuria, normal glomeruli on light microscopic examination, and negative immunofluorescence were studied to characterize the ultrastructural changes of the glomerular basement membrane. Three groups of patients were identified. Four patients (group 1) had typ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(83)80180-4
更新日期:1983-11-01 00:00:00
abstract::A 60-year-old man developed a widely metastatic spindle cell neoplasm with admixed osteoclast-like giant cells indistinguishable from malignant giant cell tumor of soft parts. Autopsy revealed a bronchogenic sarcomatoid squamous cell carcinoma that was the primary source of the sarcomatoid metastases. The osteoclast-l...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(83)80181-6
更新日期:1983-11-01 00:00:00